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Find High-Paying Python Developer Jobs ($80K-$200K+)

Django · Flask · FastAPI · Remote & Onsite · Updated daily · No recruiter spam
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👑 Remote Principal Python Developer Jobs

Principal Django engineer positions for senior technical leaders.
📊 175 open positions 🌐 Remote Only

Staff Data Scientist

Duck Duck Go
Worldwide
Remote
Full Time
Sep 26, 2026

Senior Customer Engineer, Named - Toronto Canada at Cloudflare

Remote First
Worldwide
Remote
Full-time
Sep 26, 2026

Senior Customer Engineer, Central Territory - Toronto, Canada at Cloudflare

Remote First
Worldwide
Remote
Full-time
Sep 26, 2026

Senior Customer Engineer, Named - Vancouver, BC at Cloudflare

Remote First
Worldwide
Remote
Full-time
Sep 26, 2026

Lead Data Scientist - Solution Architect at MCA Connect

Remote First
Worldwide
Remote
Full-time
Sep 26, 2026

Forward Deployed AI Engineer (Python) - Remote - USA

FullStack
Worldwide
Remote
Full-time
Sep 26, 2026

Forward Deployed AI Engineer (Python) - Remote - USA

FullStack
Worldwide
Remote
Full-time
Sep 26, 2026

Forward Deployed AI Engineer (Python) - Remote - USA

FullStack
Worldwide
Remote
Full-time
Sep 25, 2026

Staff Data Engineer (Remote in Brazil) at KnowBe4

Remote First
Worldwide
Remote
Full-time
Sep 25, 2026

Principal Software Engineer, AI

$165,000-185,000
Salesloft
United States
Remote
Full-Time
Sep 25, 2026

Senior Software Engineer I (Observability Platform) at Smartsheet

Remote First
Worldwide
Remote
Full-time
Sep 25, 2026

Principal Customer Engineer, Central Majors - Toronto Canada at Cloudflare

Remote First
Worldwide
Remote
Full-time
Sep 25, 2026

AI Engineer at Hyperproof

Remote First
Worldwide
Remote
Full-time
Sep 25, 2026

Solutions Architect - MENA

Deepgram
Worldwide
Remote
Full-Time
Sep 25, 2026

Principal Product Data Scientist

Tripadvisor
Poland
Remote
Full-Time
Sep 25, 2026

Senior Biostatistician at Freenome

Remote First
Worldwide
Remote
Full-time
Sep 24, 2026

Principal Data Visualization Engineer (Qlik) at Dev Technology Group, Inc.

Remote First
Worldwide
Remote
Full-time
Sep 24, 2026

Principal Mechanical Engineer (Starship) at SpaceX

Remote First
Worldwide
Remote
Full-time
Sep 24, 2026

Research Engineer at Invisible Technologies

Remote First
Worldwide
Remote
Full-time
Sep 23, 2026

Principal - Python Engineer

Mindera
Canada
Remote
Full-time
Sep 23, 2026

About Remote Principal Python Developer Jobs

Principal Django engineer positions for senior technical leaders.

These 175 Python developer jobs match Principal experience levels. Every listing shows the salary range when the employer publishes one, so you can compare offers before you apply.